Top 5 Most Read RNS's on Vox Markets for Tuesday 25th April 2023
Episode 1359, Apr 25, 2023, 07:01 AM
Top 5 Most Read RNS's on Vox Markets for Tuesday 25th April 2023
1. Avacta Group #AVCT - Preliminary Results
Avacta's lead pre|CISION™ programme, AVA6000 - a tumour microenvironment activated form of a chemotherapeutic agent, doxorubicin:
The first-in-human Phase 1 clinical trial (ALS-6000-101) progressed through the dosing of four cohorts (80 mg/m2 up to 200 mg/m2) following positive reviews of safety and tolerability data.
Revenues of £9.7 million (2021: £2.9 million).
Operating loss of £32.6 million (2021: £29.1 million).
Cash and short-term deposit balances at 31 December 2022 of £41.8 million (31 December 2021: £26.2 million).
2. hVIVO #HVO - Final results
Revenue up 30% to £50.7m (2021: £39.0m)
EBITDA increased threefold to £9.1m (2021: £2.9m)
Cash and cash equivalents of £28.4m as at 31 December 2022 (2021: £15.7m)
3. Guild Esports #GILD - Sponsorship deal signed with hummel
Guild Esports announce it has signed a three-year sponsorship and merchandising deal with Hummel International Sport & Leisure, a leading global sports and fashion brand and manufacturer of high-quality sportswear.
The sponsorship will generate up to £700,000 of revenues for the Company over the duration of the contract
4. N4 Pharma PLC - siRNA update
Nigel Theobald, Chief Executive Officer of the Company, commented:
"We are very pleased with these in vitro results for Nuvec® loaded with EGFR and BCL-2, which show that the first investigated dose produces comparable cellular apoptosis to two commercially available products.
"We also now have the assay established to complete the dose response expression work for BCL-2, but we already know that BCL-2 must be expressed, as the cell apoptosis work has shown that it knocks down the gene to produce cell death."
5. Canadian Overseas Petroleum #COPL - Conversion of Bonds and Share Issuances
The Company has issued 4,895,960 common shares pursuant to conversions of $0.2 million principal of 2027 Bonds and $0.2 million principal of 2028 Bonds. Following these conversions, COPL's outstanding bonds include:
2027 Bonds principal outstanding: $15.8 million (79 bonds)
2028 Bonds principal outstanding: $17.2 million (86 bonds)